Suppression of cytidylate biosynthesis by protein synthesis antagonists.

‏‎suppression of coke formation in thermal cracking by coke inhibitors‎‏

‏‎the main purpose of this research was to:1.develop a coking model for thermal cracking of naphtha.2.study coke inhibition methods using different coke inhibitors.developing a coking model in naphtha cracking reactors requires a suitable model of the thermal cracking reactor based on a reliable kinetic model.to obtain reliable results all these models shall be solved simultaneously.for this pu...

Suppression of Aldosterone Synthesis and Secretion by Ca2+ Channel Antagonists

Aldosterone, a specific mineralocorticoid receptor (MR) agonist and a key player in the development of hypertension, is synthesized as a final product of renin-angiotensin-aldosterone system. Hypertension can be generally treated by negating the effects of angiotensin II through the use of angiotensin-converting enzyme inhibitors (ACE-Is) or angiotensin II type 1 receptor antagonists (ARBs). Ho...

De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin.

Aspirin affords cardioprotection through the acetylation of serine529 in human cyclooxygenase-1 (COX-1) of anucleated platelets, inducing a permanent defect in thromboxane A2 (TXA2)-dependent platelet function. However, heterogeneity of COX-1 suppression by aspirin has been detected in cardiovascular disease and may contribute to failure to prevent clinical events. The recent recognized capacit...

Suppression of Metalloproteinase Biosynthesis

To study the interaction of lymphocytes and macrophages in the control of extracellular matrix turnover, we determined the effects ofseveral solubleT cell products on mononuclear phagocyte production of metalloproteinases. Cytokines including IL2, IL4, IL-6, tumor necrosis factor a (TNFa), GM-CSF, and IFN-gamma were each tested for capacity to modulate macrophage metalloproteinase and tissue in...

Suppression of Floral Induction by Inhibitors of Steroid Biosynthesis.